How Vitamin D interacts with rifampin

Interaction type: Depletions

Interaction rating: Study Supported

A study showed that patients taking rifampin (600 mg/day) for 2 weeks had a 70% decrease in blood levels of vitamin D. Supplementation with the affected nutrient may be necessary. (1)


  1. View Abstract: Brodie MJ, et al. Rifampicin and Vitamin D Metabolism. Clin Pharmacol Ther. June1980;27(6):810-14.