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Conservation

Compilation of herbal plants (description, geographical distribution, taxonomy, line drawings), biodiversity and herbarium.

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Research & Publication

Description of herbal and T&CM research, searchable publication and process from medicinal plant discovery to clinical trial in producing a high-quality registered herbal drug.

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Traditional & Complementary Medicine (T&CM)

 

Definition and description of therapies, policy, training and education, research in the practise of (T&CM) and integrated medicine system.           

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News Update

Announcement & Advertisement

Forthcoming Events

International Conference on Biotechnology and Healthcare

From Mon, 7. December 2020 Until Tue, 8. December 2020

International Conference on Malay Medical Manuscript

From Tue, 15. December 2020 Until Wed, 16. December 2020

International Conference on Natural Medicine and Nutrition (ICNMN) 2020

From Thu, 17. December 2020 Until Fri, 18. December 2020

1st Global Summit on Generic Drugs and Quality Control

From Fri, 22. January 2021 Until Sat, 23. January 2021

International Conference on Natural Products and Drug Discovery (ICNPDD) 2021

From Thu, 11. February 2021 Until Fri, 12. February 2021

How Folic Acid interacts with Anticonvulsants

Interaction type: Depletions

Interaction rating: Study Supported

Anticonvulsants are reported to decrease levels of folic acid in the body. Supplementation with the affected nutrient may be necessary, but if you are using any of these medications please see your healthcare professional before taking a folic acid supplement. (1) (2) (3) (4) (5)

These drugs include phenytoin, carbamazepine, primidone, gabapentin, valproic acid, felbamate, lamotrigine, mephenytoin, fosphenytoin, clonazepam, ethosuximide, diazepam, clorazepate dipotassium, levatiracetam, tiagabine, topiramate, methsuximide, phensuximide, trimethadione, magnesium sulfate, acetazolamide, oxcarbazepine, zonisamide, ethotoin

References

  1. View Abstract: Kishi T, et al. Mechanism for Reduction of Serum Folate by Antiepileptic Drugs during Prolonged Therapy. J Neurol Sci. Jan1997;145(1):109-12.
  2. View Abstract: Carl GF, et al. Phenytoin-folate Interactions: Differing Effects of the Sodium Salt and the Free Acid of Phenytoin. Epilepsia. Apr1992;33(2):372-75.
  3. View Abstract: Carl GF, et al. Effect of Chronic Primidone Treatment on Folate-dependent One-carbon Metabolism in the Rat. Biochem Pharmacol. Jul1987;36(13):2139-44.
  4. View Abstract: Hendel J, et al. The Effects of Carbamazepine and Valproate on Folate Metabolism in Man. Acta Neurol Scand. Apr1984;69(4):226-31.
  5. View Abstract: Seligmann H, Potasman I, Weller B, et al. Phenytoin-folic acid interaction: a lesson to be learned. Clin Neuropharmacol. Sep1999;22(5):268-72.

Explore Further

Consumer Data

Consumer data including medicinal herbs, dietary supplement monographs, health condition monographs and interactions and depletions.                                    

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Professional Data

Professional data organized into medicinal herbs, dietary supplement monographs, health condition monographs, T&CM herbs, formulas, health conditions, interactions and depletions.

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International Data

We offer International linkages to provide extensive content pertaining to many facets of T&CM as well as Integrated Medicine. Please register for access.    

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