How Folic Acid interacts with Corticosteroid medications

Interaction type: Depletions

Interaction rating: Study Supported

Corticosteroids have been reported to decrease the amount of folic acid in the blood. Supplementation with the affected nutrient may be necessary. (1)

These drugs include prednisone, hydrocortisone, methylprednisolone, prednisolone, betamethasone, budesonide, triamcinolone, dexamethasone, cortisone, beclomethasone, flunisolide, fluticasone, fludrocortisone, mometasone


  1. Roe DA. Handbook Interactions of Selected Drugs and Nutrients in Patients. 3rd Edition. Chicago: The American Dietetic Association; 1984:89.