How Folic Acid interacts with sulfasalazine

Interaction type: Depletions

Interaction rating: Study Supported

Animal studies have shown that this medication interrupts the use of folic acid in the body. Supplementation with the affected nutrient may be necessary. (1)

References

  1. View Abstract: Baggott JE, et al. Inhibition of Folate-dependent Enzymes by Nonsteroidal Anti-Inflammatory Drugs. Biochem J. 1992;282(Pt 1):197-202.