How Eicosapentaenoic Acid (EPA) interacts with Anticoagulant medications

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Studies have reported that EPA affects the blood's clotting ability and may alter the effects of these medications and possibly the dose needed for treatment. Use with caution. (1) (2)

These drugs include warfarin, heparin, dalteparin, tinzaparin, enoxaparin, danaparoid sodium, antithrombin III, lipirudin, argatroban, bivalirudin,


  1. View Abstract: Dyerberg J, Bang HO. A Hypothesis on the Development of Acute Myocardial Infarction in Greenlanders. Scand J Clin Lab Invest Suppl. 1982;161:7-13.
  2. View Abstract: Tamura Y, Hirai A, Terano T, Saitoh H. Anti-thrombotic and Anti-atherogenic Action of Eicosapentaenoic Acid. Nippon Rinsho. Feb1992;50(2):403-7.