How Coenzyme Q10 (CO-Q10) interacts with Anticoagulant medications

Interaction type: Interactions

Interaction rating: Case Study Support

There have been several case reports where coenzyme-Q10 reportedly upset coagulation times that had been stabilized with warfarin. Coenzyme-Q10 is reported to have anticoagulant activity. These agents should not be taken together without close medical supervision. (1) (2)

These drugs include warfarin, heparin, dalteparin, tinzaparin, enoxaparin, danaparoid sodium, antithrombin III, lipirudin, argatroban, bivalirudin,


  1. View Abstract: Heck AM, DeWitt BA, Lukes AL. Potential Interactions Between Alternative Therapies and Warfarin. Am J Health Syst Pharm. Jul2000;57(13):1221-7.
  2. View Abstract: Landbo C, Almdal TP. Interaction Between Warfarin and Coenzyme Q10. Ugeskr Laeger. May1998;160(22):3226-7