How Beta-Carotene interacts with Proton pump inhibitors

Interaction type: Interactions

Interaction rating: Proven

Based on Pharmacology: By lowering gastric acid secretion, omeprazole may cause a significant reduction in the absorption of beta-carotene. Supplementation with the affected nutrient may be necessary. (1)

These drugs include lansoprazole, omeprazole, rabeprazole, pantoprazole, esomeprazole


  1. View Abstract: Tang G, Serfaty-Lacrosniere C, Camilo ME, et al.Gastric Acidity Influences the Blood Response to a Beta-carotene Dose in Humans. Am J Clin Nutr. Oct1996;64(4):622-6.