How Calcium interacts with cholestyramine

Interaction type: Depletions

Interaction rating: Proven

Cholestyramine causes increased urinary excretion of calcium, which can cause a net negative calcium balance. Supplementation with the affected nutrient may be necessary. (1)


  1. View Abstract: Watkins DW, et al. Alterations in Calcium, Magnesium, Iron, and Zinc Metabolism by Dietary Cholestyramine. Dig Dis Sci. 1985;30(5):477-82.