How Calcium interacts with Corticosteroid medications

Interaction type: Depletions

Interaction rating: Proven

Studies indicate that corticosteroids cause decreased calcium absorption and increased urinary calcium excretion. Supplementation with the affected nutrient may be necessary. (1) (2)

These drugs include prednisone, hydrocortisone, methylprednisolone, prednisolone, betamethasone, budesonide, triamcinolone, dexamethasone, cortisone, beclomethasone, flunisolide, fluticasone, fludrocortisone, mometasone


  1. View Abstract: Reid IR, et al. Evidence for Decreased Tubular Reabsorption of Calcium in Glucocorticoid-treated Asthmatics. Horm Res. 1987;27(4):200-04.
  2. View Abstract: Adachi JD, Ioannidis G. Calcium and vitamin D therapy in corticosteroid-induced bone loss: what is the evidence? Calcif Tissue Int. Oct1999;65(4):332-6.