How Calcium interacts with Aluminum and magnesium containing antacids

Interaction type: Depletions

Interaction rating: Proven

Magnesium and aluminum-containing antacids can cause an increased excretion of calcium. Supplementation with the affected nutrient may be necessary. (1)

These drugs include aluminum hydroxide, aluminum carbonate, magnesium carbonate, magnesium hydroxide, magnesium oxide, magnesium trisilicate, aluminum magnesium hydroxide sulfate


  1. View Abstract: Weberg R, et al. Mineral-metabolic Side Effects of Low-dose Antacids. Scand J Gastroenterol. Aug1985;20(6):741-46.