How Calcium interacts with iron

Interaction type: Interactions

Interaction rating: Proven

Calcium competitively inhibits the absorption of both heme and non-heme iron. This is likely due to inhibition of the mucosal cellular transport of iron into the bloodstream. This interaction may alter the effects of iron and possibly the dose needed for treatment. (1)


  1. View Abstract: Hallberg L, Rossander-Hulthen L, Brune M, et al. Inhibition of haem-iron absorption in man by calcium. Br J Nutr. Mar1993;69(2):533-40.