Magnesium in Coronary Heart Disease.




American Journal of Cardiology,

Related Monographs

Consumer Data: Magnesium
Professional Data: Magnesium


Magnesium is involved in the interaction of more than 300 enzyme reactions in the body. It is necessary for the transmission of nerve impulses, temperature regulation, detoxification, energy production and the formation of healthy bones and teeth. In addition, it is required for metabolism of carbohydrates, proteins and fats. As part of its role in the activity of enzymes, it is involved in the transmission of nerve impulses and muscle contractions. It is also vital for cardiovascular health. Good food sources include nuts, legumes, cereal grains, and dark green leafy vegetables.

A U.S. Department of Agriculture study found that 75 percent of Americans do not get an adequate supply of magnesium in their diet. This is probably due to the absence of magnesium in many processed foods and the depletion of magnesium from agricultural soils in the U.S.

Published in the American Journal of Cardiology, authors stated that the risk of coronary heart disease (CHD) and dietary magnesium (Mg) intake have not properly been identified. As part of the Honolulu Heart Program, during 1965 and 1968, 7,172 men were questioned about magnesium intake. After a follow up of 30 years, there were 1,431 cases of CHD. The lowest magnesium group had an intake of 50.3 mg to 186 mg of magnesium daily, and the highest ranged from 340 mg to 1183 mg daily. After adjustments for age and other nutritional factors, the results showed that when compared to the higher intake group, those in the lower group had a higher risk of CHD. Although the authors stated that further studies are needed, they concluded that, “dietary Mg is associated with a reduced risk of CHD.”1


1. Abbott Rd, et al. Dietary magnesium intake and the future risk of coronary heart disease (The Honolulu Heart Program). Am J Cardiol. Sep 2003;92(6):665-9.