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Acalypha siamensis Oliv.

Synonyms

Acalypha evrardii Gagn.,  Acalypha sphenophylla Pax & K.Hoffm.

Vernacular Names:

Malaysia: Teh Hutan, Teh Kampong, Tumpat
Indonesia:  Teh Hutan, Teh Kampong, Daun Renda, Akalipa
Thailand:  Cha khoi(Northern); cha yuan, ka nam(Bangkok); cha ruesi (Central); phak duk, phak dut (Prachuap Khiri Khan); cha pa (Pattani)
Cambodia:  Tae

General Information

Description

Acalypha siamensis is a member of the Euphorbiaceae family and native of Southern Thailand and Northern Peninsular Malaysia. It is a shrub of 0.5-5m high, freely branching with branches longitudinally fissured, and pubescent when young. Stipules are narrowly triangular, 2-2.5mm long, pubescent and with glandular hair. The leaves have short petiole 0.1-0.87cm long, longitudinally grooved above, pubescent. The blade is rhomboid, 2-7 x 3.5cm, coriaceous with cuneate base and crenulate-serrated margins; apex is acute or obtuse, glabrous on both surfaces; nerves are 4 or 5 pairs. Inflorescences single together, bisexual or only staminate or pistillate flowers. They appear at the axilla, 3-6cm long with staminated part apically while the pistillate part at the base. Fruits are 3-lobed obvate, 3-5 x 4-7mm, armed with unsharp thorns with an apical, caducous gland. Seeds are ovoid or subglobular, 2-3 x 2-2.5mm.

Plant Part Used

Leaves

Chemical Constituents

Acalyphaser A

Traditional Use:

In South-east Asia it is used as tea. Malaysians used to treat fever and renosis. [1] Indonesians believe it is diuretic and also promotes healing of wounds. [2]

Pre-Clinical Data

Pharmacology

Antimicrobial activity

Four fractions (hexane, dichloromethane, ethyl acetate and methanol) of the leaf extracts of A. siamensis were evaluated for their antibacterial and antifungal activity. It was found that the ethyl acetate and methanol extracts showed pronounced antibacterial activity while none of the extracts had any antifungal activity. [3] 

Cytotoxic activity

In a study of five Malaysian plant species for their cytotoxicity, studies found A. siamensis exhibited the strongest growth inhibition. They isolated a novel tetraterpene, acalyphaser A which they believe to be responsible for the anticancer activity. [4] 

Toxicities

No documentation

Clinical Data

Clinical Trials

No documentation

Adverse Effects in Human:

No documentation

Use in Certain Conditions

Pregnancy / Breastfeeding

No documentation

Age Limitations

Neonates / Adolescents

No documentation

Geriatrics

No documentation

Chronic Disease Conditions

No documentation

Interactions

Interactions with drugs

No documentation

Interactions with Other Herbs / Herbal Constituents

No documentation

Contraindications

Contraindications

No documentation

Case Reports

No documentation

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  1) Botanical Info

References

  1. Timothy Johnson CRC ethnobotany desk reference CRC Press LLC Boca Raton 1999 pg. 6.
  2. Juwita Ratnasari, SP, Ir. Krisantini PhD Panduan Praktis Mengenal Keunikan, 767 Jenis, Galeri Tanaman Hias Daun Penebar Swadaya Jakarta 2008 pg 31.
  3. Wiart C, Hannah A, Yassim M, Hamimah H, Sulaiman M. Antimicrobial activity of Acalypha siamensis Oliv. ex Gage. J Ethnopharmacol. 2004 Dec;95(2-3):285-6.
  4. Kambara H, Yamada T, Tsujioka M, Matsunaga S, Tanaka R, Ali HI, Wiart C, Yusof M, Hassan H, Hanifah A, Fauzi ZM, Mazlan NH, Jay M, Kunishima M, Akaho E. A study on medicinal plants from Malaysia focused on Acalypha siamensis Oliv. ex Gage. isolation and structure of a new tetraterpene, acalyphaser A. Chem Biodivers. 2006 Dec;3(12):1301-6. 

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