Functions
The formula helps to replenish essence, supplement marrow, reinforce the kidney, and strengthen yang. It is used to treat body weakness, kidney deficiency, sexual impotence, spermatorrhea, and dark, dense urine.
Dosage Info
Pill: orally taken, 30mg, once a day. Tablet: 6 tablets, 3 times a day.5:1 concentrated extract: 9grams/day.
Ingredients
Precautions
Patients with allergic reactions caused to alcohol should take this formula with caution.
Pharmacology
Effect on lipid metabolism in rats with alcohol induced liver injuries: Wu Zhi Yan Zong Wan (1-2g/kg) can significantly protect alcohol-induced liver injuries by preventing the reduction of serum total cholesterol and the increase of serum and liver triglycerides in rats. It can also significantly alleviate changes in fat degeneration of the liver and necrosis of liver tissue (P
Clinical Applications
Treating sexual impotence
Lin Yu Qun, et al. used Wu Zi Yan Zong Wan to treat sexual impotence caused by panic induced kidney injury. The principles used for the treatment were warming and recuperating the kidney-yang, regulating the flow of qi, and tranquilizing the mind. They achieved satisfactory results. (1)
Treating recurrent mouth ulcers
Wu Zi Yan Zong Wan was used to treat 50 cases of recurrent mouth ulcers at a dosage of 6g, 3 times a day. Fifteen days constituted one course of treatment. The patients continued to take the formula at the attack stage and at intermission. During administration patients remained relaxed, restricted eating and drinking, led a regular life, and did not eat pungent, fatty, or sweet foods. The results showed recovery in 38 cases, improvement in 8 cases, and no improvement in 4 cases. The total effectiveness rate was 92%. (2)
Treating uterine hypoplasia
Pang Yu Qin used Wu Zi Yan Zong Wan to treat hypoplasia of uterus. The formula consisted of Sha Wan Zi (Flatstem), Tu Si Zi (Dodder Seed), Gou Qi Zi (Wolfberry Fruit), Che Qian Zi (Plantain Seed), and Fu Pen Zi (Rubus). Shan Zhu Yu (Dogwood Fruit) and Dang Gui (Chinese Angelica Root) were added for deficiency of yin and blood. Ren Shen (Ginseng) was added for deficiency of qi. Xiang Fu (Cyperus Tuber) and Yu Jin (Curcuma Root) were added for depression. The decoction was taken orally one dose a day from the second day of menstruation to the first day of the next menstruation. After two menstrual cycles, the decoction was then taken for 4 months as one course of treatment from the 7th to 17th day of menstruation. 1 to 3 courses of treatment resulted in full recovery in 68 cases, improvement in 21 cases, and no improvement in 11 cases. The total effectiveness rate was 89%. (3)
Treating infertility
Modified Wu Zi Yan Zong Wan and a medicinal meal for promoting the generation of vital essence were used to treat male infertility. The formula was modified according to the individual’s symptoms. This formula consisted of Gou Qi Zi (Wolfberry Fruit), Tu Si Zi (Dodder Seed), Fu Pen Zi (Raspberry), Wu Wei Zi (Schisandra Fruit), Che Qian Zi (Plantain), Jin Yin Zi (Cherokee Rose-hip), Sang Shen Zi (Mulberry), and Xian Lin Pi (Epimidium). The decoction was taken orally daily for 1 month. The medicinal meal for promoting the generation of vital essence was eaten in the morning and in the evening. One month constituted one course of treatment. The results showed full recovery for 28 cases, improvement in 13 cases, and no improvement in 8 cases. The total effectiveness rate was 83.7%. (4)
References
- Lin You Qun, et al. Treating 95 cases of male reproductive function decrease with differential diagnosis. Journal of Anhui College of TCM. 1990;9(3):25-26.
- Li Hong Yi, et al. Therapeutic observation on treating 50 cases of recurrent stomatocace with Wu Zi Yan Zong Wan. Hebei Journal of TCM. 1999;21(4):227.
- Pang Yu Qin. Treating 100 cases of uterine hypoplasia with Wu Zi Yan Zong Wan. Henan Journal of TCM Pharmacy. 1995;10(6):43-44.
- Liu Zuo Wen. Treating 49 cases of male infertility with modified Wu Zi Yan Zong Wan combined with a medicinal meal for promoting the generation of vital essence. Journal of Popular Medicine of Chinese Ethnic Minorities. 1999;(6): 327-329.
