Xi Feng Ding Xian Wan

Functions

Xi Feng Ding Xian Wan mainly functions to arouse patients from unconsciousness by clearing away heat and to relieve arrest convulsion by dispelling phlegm. It is used to treat symptoms induced by accumulation and stagnation of phlegm and saliva, such as epilepsy and convulsion, discharge of frothy saliva from the mouth, opisthotonus, blank stares, and spasm in the limbs.

Dosage Info

Internal administration, 5:1 concentrated extract: 9 grams/day

Ingredients

Precautions

Toxicity: LD50 (mice/intraperitoneal injection): 76.06 ± 9.24g/kg. (1)

Pharmacology

Anti-convulsive effect: Experiments show that administered to mice by intraperitoneal injecton at various dosage levels, extract of Xi Feng Ding Xian Wan can enhance bentoin’s inhibitory effect on electricity-induced convulsion. Combined use of bentoin and extract of Xi Feng Ding Xian Wan can lengthen the latency of cardiazol-induced convulsion in mice and can delay the occurrence of strychnine-induced convulsion in mice and prolong their survival time. Extract of Xi Feng Ding Xian Wan can decrease the severity of auditory convulsion in rats. (2)

Inhibiting the central nervous system: Experiments show that Xi Feng Ding Xian Wan can inhibit mice’s autonomous activity, enhance sodium barbiturate’s central inhibitory effect. The formula is effective in suppressing aggressive behavior in mice that live alone. (3)

Clinical Applications

Epilepsy
The formula is mainly used to treat different types of epilepsy. One study treated 35 cases of various types of epilepsy and reported an effective rate of 72.2%. (4)

References

  1. Jin Gui Zhen, et al. Xi Feng Ding Lan Wan’s effect on the central nervous system. China Bulletin of Pharmacology. 1989;6(1):34-35.
  2. Jin Gui Zhen, et al. Anti-convulsive effects of Xi Feng Ding Lan Wan. China Bulletin of Pharmacology. 1989;6(1):32-34.
  3. Jin Gui Zhen, et al. Xi Feng Ding Lan Wan’s effect on the central nervous system. China Bulletin of Pharmacology. 1989;6(1):34-35.
  4. Jin Gui Zhen, et al. Anti-convulsive effects of Xi Feng Ding Lan Wan. China Bulletin of Pharmacology. 1989;6(1):32-34.