Yin Qiao San

Functions

According to traditional Chinese medicine, this formula of a pungent flavor is cool in property, and it clears away heat and cleanses toxic material. It treats the wind-heat type of the common cold, and epidemic febrile diseases still in the incipient stage, when the patient runs a fever but does not have an adversion to coldness or has only a slight adversion to coldness, and suffers from thirstiness, headache, coughing, and sore swollen throat.

Dosage Info

Bolus: each bolus weighs 3 g, 1 bolus each time, 2-3 times a day. Taken with warm boiled water, or Lu Gen Tang. Tablet: 16 tables per bag, 4 tablets each time, 2-3 times a day. Infusion: infuse with boiled water, 1 bag each time, 3 times a day. 5:1 concentrated extract: 9 grams/day.

Ingredients

Precautions

Toxicity: LD50: 100g/kg (oral/decoction) and 75g (oral/tablets) (1)

Pharmacology

Inducing diaphoresis: Oral feeding this formula to rats can increase sweating in the toes area, with the minimum effective concentration being 0.267g/kg, the half-life period of the effect being 3.90 hours, the effective cycle being 23.71 hours, and the effect peaking time being 2.21 hours. (2)

Reducing fever: Experiments show that oral administration of this formula can significantly reduce bigeminal vaccine- and pentageminal vaccine-induced fever in rabbits, with the effect being of no significant difference from that of the group treated with compound aspirin (0.2mg/kg). (3) , (4)

Countering pathogenic microorganism: Both the formula as a whole and its individual ingredients have an inhibitory effect externally on several bacteria and viruses. (5) , (6) , (7)

Anti-inflammatory: The formula has a significant inhibitory effect on experimental inflammation in animals. In terms of inhibiting dimethylbenzene-induced increase in skin capillary permeability, the effect of orally-administered Yin Qiao San is measured as follows: minimum anti-inflammatory dose: 1.5g/kg; half-life period of effect: 4.53 hours; duration of effect: 16.23 hours; and effect peaking time: 2.31 hours. (8)

Analgetic: As indicated in hot plate and acetic torsion experiments on mice, this formula has an analgetic effect. (9)

Antiallergic: Oral feeding rats and mice the teabag form of this formula (10g/kg) has a significant inhibitory effect on their Radix Trichosanthis-induced skin allergic reaction. Further, a variety of forms of this formula (e.g, decoction, tablets, and teabags) are shown to have an inhibitory effect on dinitrochlorobenzene-induced otic skin delayed hypersensitivity in mice. (10)

Enhancing the immune system: Experiments show that this formula can significantly promote the phagocytic function of mice’s abdominal macrophage. (11)

Miscellaneous: This formula is shown to have a significant inhibitory effect on intestinal hyperperistalsis in animals. (12)

Clinical Applications

The common cold
 A study treated 1,150 common cold cases treated with the coarse powder form of this formula and reported the results as follows: after one day of treatment, fever was reduced across the board, the less severe cases diminished, and the more severe cases experienced quick alleviation of symptoms while taking a somewhat longer time to recover fully; on average, all cases recovered in 2.7 days. (13)

Influenza
 Of 50 flu cases treated with this formula in a study, all cases showed a speedy decrease in body temperature, self-reported significant improvement in symptoms, and resolved in two to four days. (14)

In another study, this formula was given to 1,480 people as a preventive measure against influenza (treated with 1-2 pills daily for 1.5 months) and the results were: the treatment group had a flu contraction rate of 2.6%, while the comparison group had one of 17.55%. (15)

Pneumonia
 Various studies have reported the effectiveness of treating lobar pneumonia and pneumonia. (16) , (17) , (18)

Encephalitis B
 A study used a variation of this formula was used to treat 37 cases of mild epidemic encephalitis B and reported satisfactory results in all cases. (19)

Another study treated 81 cases of epidemic encephalitis with this formula and reported the results as follows: 74 cases resolved and 6.1% died of the disease; the temperature returned to normal within 1-2 days in 21 cases, within 3-5 days in 59 cases, and after 7 days in 1 case. (20)

Parotitis
 This formula was used to treat 130 cases of parotitis with excellent results, including decreasing complications. (21)

Measles, isthmus herpes, and German measles
 A number of studies have confirmed the effectiveness of treating measles, isthmus herpes, and German measles with this formula. (22) , (23) , (24)

References

  1. Deng Wen Long. Journal of Traditional Chinese Medicine. 1986;(3):59.
  2. Fu Hang Yu, et al. Journal of Pharmacology and Clinical Application. 1992;8(5):1.
  3. Xu Jun Jie, et al. Chinese Medicine Bulletin. 1986;(1):51.
  4. Shen Ying Jun, et al. Journal of Pharmacology and Clinical Application. 1987;(Suppl):14.
  5. Zhang Jing Kai. Journal of Chinese Patent Medicine. 1981;(9):22.
  6. Wang Shou Liang, et al. Journal of Medical Science of China. 1958;(3):275.
  7. Shanghai Health and Epidemic Prevention Station. Shanghai Journal of Chinese Medicine. 1960;(2):68.
  8. Fu Hang Yu, et al. Journal of Pharmacology and Clinical Application. 1993;(1):1.
  9. Zhou Yuan Peng, et al. Chinese Patent Medicine. 1990;(1):22.
  10. Deng Wen Long. Journal of Traditional Chinese Medicine. 1986;(3):59.
  11. Deng Wen Long. Journal of Traditional Chinese Medicine. 1986;(3):59.
  12. Fu Hang Yu, et al. Chinese Patent Medicine. 1993;(1):35.
  13. Peng Yu Lin. Guangdong Journal of Traditional Chinese Medicine. 1962;(5):25.
  14. Group of Infectious Diseases. Journal of Changchun Medical College. 1959;(1):119.
  15. Han Da Wei. Journal of Traditional Chinese Medicine. 1957;(12):653.
  16. Yang Chun. Fujian Journal of Chinese Medicine. 1964;(5):16.
  17. Zhou Ling Hua. Journal of Traditional Chinese Medicine. 1959;(2):31.
  18. Sha Xing Tan. Journal of Traditional Chinese Medicine. 1959;(2):36.
  19. Liu Zhi Ming, et al. Journal of Traditional Chinese Medicine. 1958;(4):251.
  20. Wu Hao Ran, et al. Zhejiang Journal of Traditional Chinese Medicine. 1965;(8):4.
  21. Li Cheng Zhi. Shangdong Journal of Medicine. 1959;(9):34.
  22. Military General Hospital of Beijing. Current Issues of Traditional Chinese Medicine. 1958;(3):9.
  23. Wu Jin Ming. Journal of Pediatrics of China. 1963;(5):125.
  24. Wang Fa Yun. Journal of Traditional Chinese Medicine. 1987;(4):33.