Isolated diastolic dysfunction of the myocardium and its response to CoQ10 treatment.
Author Langsjoen PH, Langsjoen PH, Folkers K Date 1993 Journal Clin Investig Abstract Symptoms of fatigue and activity impairment, atypical precordial pain, and cardiac arrhythmia frequently precede by years the development of congestive heart failure. Of 115 patients with these symptoms, 60 were diagnosed as having hypertensive cardiovascular disease, 27 mitral valve prolapse syndrome, and […]
Flow-cytometric studies with eleutherococcus senticosus extract as an immunomodulatory agent.
Author Bohn B, Nebe CT, Birr C Date 10/1987 Journal Arzneimittelforschung Abstract A placebo-controlled study of the effect of an Eleutherococcus senticosus extract (Eleukokk) on the immune system was performed with 36 healthy volunteers utilising quantitative multi-parameter flow cytometry with monoclonal antibodies directed against specific surface markers of human lymphocyte subsets. Volunteers in the verum […]
Estrogen replacement therapy: An overview
Author Mishell DR Date 1989 Journal Am J Obstet Gynecol Abstract Levels of circulating estrogen fall during the perimenopausal period, resulting in changes in the postmenopausal woman’s genitourinary tract, central nervous and cardiovascular systems, skin, and bone. Exogenous estrogen minimizes the benign symptoms and prevents the increased incidence of osteoporosis and atherosclerotic heart disease that […]
One-year treatment of obesity: a randomized, double-blind, placebo-controlled, multicentre study of orlistat, a gastrointestinal lipase inhibitor.
Author Finer N, James WP, Kopelman PG, Lean ME, Williams G. Date 3/2000 Journal Int J Obes Relat Metab Disord Abstract OBJECTIVE: To assess the efficacy and tolerability of orlistat (Xenical) in producing and maintaining weight loss over a 12-month period. DESIGN: Patients were randomized to double-blind treatment with either orlistat 120 mg or placebo […]
High prevalence of vitamin D deficiency and reduced bone mass in multiple sclerosis.
Author Nieves J, Cosman F, Herbert J, Shen V, Lindsay R Date 9/1994 Journal Neurology Abstract BACKGROUND: Female patients with multiple sclerosis (MS) are at risk for osteoporosis because of gender, immobility, and corticosteroid use. METHODS: Bone mineral density (BMD) was measured by dual x-ray absorptiometry in 80 female MS patients admitted to a tertiary […]
Effects of Ganoderma lucidum and krestin on cellular immunocompetence in gamma-ray-irradiated mice.
Author Chen WC, Hau DM, Lee SS Date 1995 Journal Am J Chin Med Abstract The effects of Ganoderma lucidum (Gl) and Krestin (PSK) extracts on cellular immunocompetence, leukocyte counts and differential count in gamma-irradiated mice were investigated in this study. ICR strain male mice were used and randomly divided into five groups. Group A […]
Effect of Gomisin A (TJN-101) on liver regeneration.
Author Kubo S, Ohkura Y, Mizoguchi Y Date 12/1992 Journal Planta Med Abstract We studied the effect of TJN-101, a lignan component of Schisandra fruits (Schisandrae fructus), on liver regeneration after partial hepatectomy. TJN-101 was given orally to male Wistar rats 30 min before partial hepatectomy. The mitotic index and the level of DNA synthesis […]
Decreased hypothalamic-pituitary-adrenal axis sensitivity to cortisol feedback inhibition in human aging.
Author Wilkinson CW, Peskind ER, Raskind MA. Date 1/1997 Journal Neuroendocrinology Abstract Aging-related reduction in the sensitivity of the hypothalamic-pituitary-adrenal (HPA) axis to glucocorticoid feedback inhibition has been demonstrated in rodents, but aging effects on glucocorticoid feedback inhibition in humans are unclear. This study assessed the influence of aging on the sensitivity of the human […]
The potential preventive effects of vitamins for cataract and age- related macular degeneration.
Author Jacques PF Date 5/1999 Journal Int J Vitam Nutr Res Abstract Age-related cataract and age-related macular degeneration (AMD) are important public health problems. Approximately 50% of the 30 to 50 million cases of blindness worldwide result from unoperated cataract. In the US and other developed countries AMD is the leading cause of blindness, but […]
A study of the effects of procyanidol oligomers on capillary resistance in hypertension and in certain nephropathies
Author Lagrue G, Olivier-Martin F, Grillot A Date 18/9/1981 Journal Sem Hop Abstract The effects of procyanidol oligomers on capillary resistance disorders in hypertensive and diabetic patients were studied. The drug was administered in a daily dose of 150 mg. Concordant results were obtained in two investigations as follows: during an open trial in 28 […]
