Kava pyrones and resin: studies on GABAA, GABAB and benzodiazepine binding sites in rodent brain.
Author Davies LP, Drew CA, Duffield P Date 8/1992 Journal Pharmacol Toxicol Abstract Kava, an intoxicating beverage prepared from the pepper plant Piper methysticum, is widely consumed by the indigenous peoples in the islands of the South Pacific. As the first of a series of studies on the neuropharmacological interactions of kava with CNS receptors […]
Amino acid sequence of sweet-taste-suppressing peptide (gurmarin) from the leaves of Gymnema sylvestre.
Author Kamei K, Takano R, Miyasaka A, Imoto T Date 1/1992 Journal J Biochem (Tokyo) Abstract The complete amino acid sequence of a sweet-taste-suppressing peptide, gurmarin, from the leaves of Gymnema sylvestre was determined by the Edman analysis of peptides derived from digests obtained with Staphylococcus aureus V8 protease, pyroglutamyl aminopeptidase, and lysyl endopeptidase. Gurmarin […]
Antiandrogenic effects of a flavonoid-rich fraction of Vitex negundo seeds: a histological and biochemical study in dogs.
Author Bhargava SK Date 12/1989 Journal J Ethnopharmacol Abstract The ability of the flavonoid-rich fraction (5,7,3′-trihydroxy, 6,8,4′- trimethoxy flavones) of Vitex negundo seeds to antagonize the androgen action of exogenous testosterone propionate on the male reproductive system was studied in castrated prepubertal and intact adult dog. The flavonoid-rich fraction (F) was administered 10 mg/kg i.p. […]
The Ginkgo biloba extract, EGb761, increases synaptosomal uptake of 5- hydroxytryptamine: in-vitro and ex-vivo studies.
Author Ramassamy C, Christen Y, Clostre F Date 11/1992 Journal J Pharm Pharmacol Abstract The Ginkgo biloba extract (EGb 761) added to a synaptosomal fraction prepared from mice cerebral cortex modified [3H]5-hydroxytryptamine ([3H]5-HT) uptake in a biphasic manner. Between 4 and 16 micrograms mL-1 EGb 761 increased significantly the [3H]5-HT uptake (maximum + 23%). A […]
Reduced active thyroid hormone levels in acute illness.
Author Burger A, Nicod P, Suter P, Vallotton MB Date 3/1976 Journal Lancet Abstract In acute and subacute disease the active thyroid hormones, triiodothyronine (T3) and tetraiodothyroacetic acid (tetrac), are decreased while serum-thyroxine (T4) levels tend to be slightly reduced. Conversely, the inactive metabolite, reverse triiodothyronine (reverse T3), is increased indicating a diversion of T4 […]
Oleuropein protects low density lipoprotein from oxidation.
Author Visioli F, Galli C Date 1994 Journal Life Sci Abstract The Mediterranean diet, rich in fruit, vegetables, grain, and vegetable oil (mainly olive oil) is correlated with a lower incidence of coronary heart disease (CHD). Natural antioxidants contained in the Mediterranean diet might also play a role in the prevention of cardiovascular diseases, through […]
Effects of astragalus (ASI, SK) on experimental liver injury
Author Zhang YD, Shen JP, Zhu SH, Huang DK Date 1992 Journal Yao Hsueh Hsueh Pao Abstract The saponins (ASI, SK) used in this study was extracted from the root of Astragalus membranaceous Bge and Astragalus sieversianus Pull. ASI and SK were found to protect liver from chemical injury induced by CCl4, D-galactosamine and acetaminophen […]
In vitro prolactin but not LH and FSH release is inhibited by compounds in extracts of Agnus castus: direct evidence for a dopaminergic principle by the dopamine receptor assay.
Author Jarry H, Leonhardt S, Gorkow C Date 1994 Journal Exp Clin Endocrinol Abstract Women suffering from premenstrual mastodynia often respond to stimuli of prolactin (Prl) release with a hypersecretion of this hormone. Pharmacological reduction of Prl release by dopamine agonists or treatment with extracts of Agnus castus (AC) improve the clinical situation of patients […]
Inhibition of phagocyte-endothelium interactions by oxidized fatty acids: a natural anti-inflammatory mechanism?
Author Sethi S, Eastman AY, Eaton JW Date 7/1996 Journal J Lab Clin Med Abstract Diets rich in marine fish oil may protect against cardiovascular disease. Although the mechanisms involved in such protection are not known, fish oils have been reported to exert anti-inflammatory actions. For example, dietary fish oil supplementation was observed to profoundly […]
Campylobacter infection in humans
Author Arimi SM Date 12/1989 Journal East Afr Med J Abstract Campylobacter jejuni and Campylobacter coli are now recognized as common bacterial cause of enteritis in humans. They infect the healthiest of persons resulting in a self-limiting diarrhoea often accompanied by mucus and blood in the stool. On the other hand C. fetus subsp fetus […]
