Modification of the kinetics of healing after iterative exeresis in the rat. Action of a triterpenoid and its derivatives on the duration of healing
Author Poizot A, Dumez D Date 13/3/1978 Journal C R Acad Sci Hebd Seances Acad Sci D Abstract The authors have studied the action of Titrated Extract of Centella asiatica (TECA) on the duration off healing of iterative wounds in the Rat. After repeated exeresis, the planimetric quantification of the wounds, by episcopic projection, shows […]
New findings on the efficacy and mode of action of the horse chestnut saponin escin
Author Rothkopf M, Vogel G Date 2/1976 Journal Arzneimittelforschung Abstract In order to complete previous results of the efficacy of the horse chestnut saponin escin, its activity was tested on two further models of inflammation: the rat serous peritonitis provoked by i.p. injection of formalin solution, and the rat serous pleurisy provoked by intrapleural injection […]
Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer.
Author Hausen BM Date 10/1993 Journal Contact Dermatitis Abstract The sensitizing capacity of Centella asiatica (raw extract) and its triterpenic constituents asiaticoside, asiatic acid and madecassic acid has been studied in guinea pigs. The extract itself as well as the 3 acids were found to be very weak sensitizers. Centella asiatica extract is used effectively […]
Studies on the bioavailability of zinc in humans: effects of heme and nonheme iron on the absorption of zinc.
Author Solomons NW, Jacob RA Date 4/1981 Journal Am J Clin Nutr Abstract The change in the concentration of plasma zinc after oral administration of zinc was used as the index of zinc absorption in the study of the interaction of zinc and iron in the human intestine. With zinc sulfate as the source of […]
Folic acid and cyanocobalamin levels in serum and erythrocytes during low-dose methotrexate therapy of rheumatoid arthritis and psoriatic arthritis patients.
Author Leeb BF, Witzmann G, Ogris E, Studnicka-Benke A, Andel I, Schweitzer H, Smolen JS. Date 7/1995 Journal Clin Exp Rheumatol Abstract OBJECTIVE. To compare folic acid (FA) levels in patients being treated with methotrexate (MTX) with those of untreated patients in order to investigate potential folate depletion by MTX and its possible relationship to […]
Effect of topical application of coenzyme Q10 on adult periodontitis.
Author Hanioka T, Tanaka M, Ojima M Date 1994 Journal Mol Aspects Med Abstract Topical application of Coenzyme Q10 (CoQ10) to the periodontal pocket was evaluated with and without subgingival mechanical debridement. Ten male patients with adult periodontitis participated and 30 periodontal pockets were selected. During the first 3 weeks, the patients did not receive […]
Polyphenols as cancer chemopreventive agents.
Author Stoner GD, Mukhtar H Date 1995 Journal J Cell Biochem Suppl Abstract This article summarizes available data on the chemopreventive efficacies of tea polyphenols, curcumin and ellagic acid in various model systems. Emphasis is placed upon the anticarcinogenic activity of these polyphenols and their proposed mechanism(s) of action. Tea is grown in about 30 […]
Cardiovascular effects from stimulation of 5-hydroxytryptamine receptors.
Author Saxena PR. Date 1989 Journal Fundam Clin Pharmacol Abstract The cardiovascular effects of 5-hydroxytryptamine (5-HT), consisting of bradycardia or tachycardia, hypotension or hypertension, and vasodilatation or vasoconstriction, are mediated by three main types of receptors called 5-HT1-like, 5-HT2, and 5-HT3. In intact animals 5-HT elicits a short-lasting bradycardia, accompanied by hypotension, via stimulation of […]
Alleviation of migraines with therapeutic vitamin D and calcium.
Author Thys-Jacobs S Date 11/1994 Journal Headache Abstract Two postmenopausal migraineurs who developed frequent and excruciating migraine headaches (one following estrogen replacement therapy and the other following a stroke) were treated with combination vitamin D and calcium. Therapeutic replacement with vitamin D and calcium resulted in a dramatic reduction in the frequency and duration of […]
Kava-kava extract WS 1490 versus placebo in anxiety disorders–a randomized placebo-controlled 25-week outpatient trial.
Author Volz HP, Kieser M Date 1/1997 Journal Pharmacopsychiatry Abstract 101 outpatients suffering from anxiety of non-psychotic origin (DSM- III-R criteria: agoraphobia, specific phobia, generalized anxiety disorder, and adjustment disorder with anxiety) were included in a 25- week multicenter randomized placebo-controlled double-blind trial with WS 1490, a special extract of kava-kava. In the main outcome […]
