Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids.

Author Evans BA, Griffiths K, Morton MS Date 11/1995 Journal J Endocrinol Abstract Isoflavonoids and lignans, constituents of many plant foods, have been proposed as protective agents in those populations with a low incidence of hormone-dependent cancers. They may act by their inhibition of the metabolism of growth-promoting steroid hormones. This report describes the inhibition […]

New Polyhydroxylated Triterpenes from Uncaria tomentosa

Author R. Aquino Date 1990 Journal J Nat Prod Abstract Three novel polyhydroxylated triterpenes have been isolated from Uncaria tomentosa. Their structures were established as 1, 2, and 3 by detailed spectral studies including 1H-13C correlations via long range couplings using the INAPT pulse sequence, nOeds, and 2D 1H-13C direct chemical shift correlation (HETCOR) nmr […]

Release of mast cell mediators into the jejunum by cold pain stress in humans.

Author Santos J, Saperas E, Nogueiras C, Mourelle M, Antolin M, Cadahia A, Malagelada JR. Date 4/1998 Journal Gastroenterology Abstract BACKGROUND & AIMS: The central nervous system regulates gut functions via complex interactions between the enteric nervous and immune systems. The aim of this study was to investigate whether mast cell mediators are released into […]

Multiple sclerosis: fat-oil relationship.

Author Swank RL. Date 9/1991 Journal Nutrition Abstract Between 1949 and 1984, 150 patients with multiple sclerosis consumed low-fat diets. Fat, oil, and protein intakes; disability; and deaths were determined. With a daily fat consumption less than 20.1 g/day (av 17 g/day), 31% died, and average deterioration was slight. A daily intake greater than 20 […]

Effects of gamma-linolenic acid supplementation on pregnant rats fed a zinc-deficient diet

Author Dib A, Carreau JP Date 1987 Journal Ann Nutr Metab Abstract The effects of dietary gamma-linolenic acid supplementation in the form of evening primrose oil were examined in pregnant zinc-deficient rats and subsequently in their newborn pups. This supplementation was beneficial, since it reduced pup mortality, increased mean litter size and maintained appetite throughout […]

Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo.

Author Chu DT, Wong WL, Mavligit GM Date 3/1988 Journal J Clin Lab Immunol Abstract A partially purified fraction (F3) with an estimated molecular weight of 20,000 to 25,000 derived from the traditional Chinese medicinal herb Astragalus membranaceus, was found to possess a potent immunorestorative activity in vitro. Its capacity to aborogate the local xenogeneic […]

Study of pathogenesis of age-related macular degeneration

Author Wu L, Wu DZ, Cao X Date 6/1996 Journal Yen Ko Hsueh Pao Abstract OBJECTIVES: To explore the pathogenesis of age-related macular degenerastion (AMD) for its early prevention and treatment. METHODS: The enzymes of red blood cells, levels of serum mineral elements and antiretinal antibodies were determined in AMD and controls. Electronic microscopy, immunohistochemical […]

Studies on vascular permeability in hypertension: action of anthocyanosides.

Author Detre Z, Jellinek H, Miskulin M Date 1986 Journal Clin Physiol Biochem Abstract The initial phase of renal hypertension induced by ligature of the abdominal aorta was accompanied by a transient increase in vascular permeability. This permeability increase has not the same intensity in all parts of the organism: it is greater in the […]

Inhibition by hop bract polyphenols of cellular adherence and water-insoluble glucan synthesis of mutans streptococci.

Author Tagashira M, Uchiyama K, Yoshimura T, Shirota M, Uemitsu N. Date 2/1997 Journal Biosci Biotechnol Biochem Abstract The inhibitory effect of hop bract polyphenols (HBP) on cariogenic streptococci was investigated. It was found that the high molecular weight polyphenol (estimated about 36,000-40,000) inhibited the cellular adherence of Streptococcus mutans MT8148 (serotype C) and Streptococcus […]