Triterpenes from Centella asiatica stimulate extracellular matrix accumulation in rat experimental wounds.
Author Maquart FX, Chastang F, Simeon A, Birembaut P, Gillery P, Wegrowski Y. Date 6/1999 Journal Eur J Dermatol Abstract Titrated Extract from Centella asiatica (TECA) is a drug which has been used for many years in Europe for the treatment of wound healing defects. It is a reconstituted mixture of 3 triterpenes extracted from […]
Horse chestnut seed extract–an effective therapy principle in general practice. Drug therapy of chronic venous insufficiency
Author Greeske K, Pohlmann BK Date 30/5/1996 Journal Fortschr Med Abstract Within the framework of a case observation study involving more than 800 general practitioners, more than 5,000 patients with chronic venous insufficiency (CVI) were treated with standardised horse chestnut extract and followed up at regular intervals. The evolution of the symptoms, tolerability and adverse […]
Effects of interaction of tannins with co-existing substances. VII. Inhibitory effects of tannins and related polyphenols on xanthine oxidase.
Author Hatano T, Yasuhara T, Yoshihara R Date 5/1990 Journal Chem Pharm Bull (Tokyo) Abstract The inhibitory effects of hydrolyzable tannins, condensed tannins and related polyphenols on the activity of xanthine oxidase (XOD), catalyzing uric acid formation from xanthine, were investigated. Marked differences in the strength of the inhibition were observed. Some of the differences […]
Neurologic aspects of cobalamin deficiency.
Author Healton EB, Savage DG, Brust JC Date 7/1991 Journal Medicine (Baltimore) Abstract We reviewed 153 episodes of cobalamin deficiency involving the nervous system that occurred in 143 patients seen over a recent 17- year period at 2 New York City hospitals. Pernicious anemia was the most common underlying cause of the deficiency. Neurologic complaints, […]
Hypoglycemic constituents of Panax ginseng.
Author Ng TB, Yeung HW Date 1985 Journal Gen Pharmacol Abstract This article reviews the recent progress in the identification of hypoglycemic and insulino-mimetic principles in ginseng. Hitherto five types of substances have been discovered. They include five glycans designated panaxans A to E, adenosine, a carboxylic acid, a peptide with a molecular weight of […]
Bioenergetics in clinical medicine. VI. adjunctive treatment of periodontal disease with coenzyme Q10.
Author Wilkinson EG, Arnold RM, Folkers K Date 8/1976 Journal Res Commun Chem Pathol Pharmacol Abstract Eighteen patients with periodontal disease and measurable pockets were treated on a double-blind basis with coenzyme Q10 and a maching placebo. The treatment was significant (p less than 0.01). Before decoding, all 8 patients receiving coenzyme Q10 and 7/10 […]
Inhibition by hop bract polyphenols of cellular adherence and water-insoluble glucan synthesis of mutans streptococci.
Author Tagashira M, Uchiyama K, Yoshimura T, Shirota M, Uemitsu N. Date 2/1997 Journal Biosci Biotechnol Biochem Abstract The inhibitory effect of hop bract polyphenols (HBP) on cariogenic streptococci was investigated. It was found that the high molecular weight polyphenol (estimated about 36,000-40,000) inhibited the cellular adherence of Streptococcus mutans MT8148 (serotype C) and Streptococcus […]
Hydroxocobalamin (vitamin B12a) prevents and reverses endotoxin-induced hypotension and mortality in rodents: role of nitric oxide.
Author Greenberg SS, Xie J, Zatarain JM, Kapusta DR, Miller MJ. Date 4/1995 Journal J Pharmacol Exp Ther Abstract The cobalt atom of hydroxocobalamin (OHC) binds cyanide and nitric oxide (NO) and OHC attenuates vascular responses to NO in vitro. NO mediates the hypotension of endotoxemia. Thus, we tested the postulate that OHC may attenuate […]
High-dose riboflavin as a prophylactic treatment of migraine: results of an open pilot study
Author Schoenen J, Lenaerts M, Bastings E Date 10/1994 Journal Cephalalgia Abstract If the brain of migraineurs is characterized between attacks by a reduction of mitochondrial phosphorylation potential, riboflavin, which has the potential of increasing mitochondrial energy efficiency, might have prophylactic effects in migraine. In this preliminary open pilot study, 49 patients suffering from migraine […]
Mechanism of antiinflammatory actions of curcumine and boswellic acids.
Author Ammon HP, Safayhi H, Mack T, Sabieraj J Date 3/1993 Journal J Ethnopharmacol Abstract Curcumine from Curcuma longa and the gum resin of Boswellia serrata, which were demonstrated to act as anti-inflammatories in in vivo animal models, were studied in a set of in vitro experiments in order to elucidate the mechanism of their […]
