Dosing and administration of ergotamine tartrate and dihydroergotamine.

Author Mathew NT. Date 1997 Journal Headache Abstract Ergotamine tartrate (ET) and dihydroergotamine (DHE) are effective therapies for migraine and cluster headache. Optimal management with these agents must take several factors into account, including headache type and severity, associated symptoms, side effect potential, choice of dosage forms, and appropriate dosing. Oral ET is most appropriate […]

Randomised double-blind placebo-controlled trial of feverfew in migraine prevention.

Author Murphy JJ, Heptinstall S, Mitchell JR Date 23/7/1988 Journal Lancet Abstract The use of feverfew (Tanacetum parthenium) for migraine prophylaxis was assessed in a randomised, double-blind, placebo-controlled crossover study. After a one-month single-blind placebo run-in, 72 volunteers were randomly allocated to receive either one capsule of dried feverfew leaves a day or matching placebo […]

Development of tolerance to kava in mice.

Author Duffield PH, Jamieson D Date 8/1991 Journal Clin Exp Pharmacol Physiol Abstract 1. The development of tolerance to the aqueous extract of kava, and to the lipid soluble extract (kava resin) was tested in mice. 2. Tolerance to the unknown pharmacologically active ingredient(s) developed very rapidly, given parenterally, in the aqueous extract. A minimally […]

Characteristics of antisweet substances, sweet proteins, and sweetness-inducing proteins.

Author Kurihara Y Date 1992 Journal Crit Rev Food Sci Nutr Abstract Recent studies on structures and functions of sweetness-inhibiting substances (gymnemic acid, ziziphin, and gurmarin); sweet proteins (monellin, thaumatin and mabinlin); and taste-modifying proteins (miraculin and curculin) were reviewed. Several gymnemic acid homologues and gurmarin were purified from the leaves of Gymnema sylvestre and […]

Topical capsaicin. A review of its pharmacological properties and therapeutic potential in post-herpetic neuralgia, diabetic neuropathy and osteoarthritis.

Author Rains C, Bryson HM Date 10/1995 Journal Drugs Aging Abstract Capsaicin, the active principle of hot chili pepper, is thought to selectively stimulate unmyelinated C fibre afferent neurons and cause the release of substance P. Prolonged application of capsaicin reversibly depletes stores of substance P, and possibly other neurotransmitters, from sensory nerve endings. This […]

Comparative antibacterial and antifungal effects of some phenolic compounds.

Author Aziz NH Date 1/1998 Journal Microbios Abstract The antimicrobial potential of eight phenolic compounds isolated from olive cake was tested against the growth of Escherichia coli, Klebsiella pneumoniae, Bacillus cereus, Aspergillus flavus and Aspergillus parasiticus. The phenolic compounds included p-hydroxy benzoic, vanillic, caffeic, protocatechuic, syringic, and p-coumaric acids, oleuropein and quercetin. Caffeic and protocatechuic […]

Laboratory evaluation of women experiencing reproductive failure.

Author Roussev RG Date 4/1996 Journal Am J Reprod Immunol Abstract Reproductive life table analysis indicates that the majority of reproductive failures result from post fertilization failures, whether before or after implantation. It is important to have a set of tests to clarify the diagnosis of the reproductive failure so that appropriate therapy can be […]