Raynaud’s phenomenon. An update.
Author Coffman JD Date 5/1991 Journal Hypertension Abstract The pathogenesis of primary Raynaud’s phenomenon remains an enigma. Most evidence favors a local abnormality in the digital arteries as opposed to an increased activity of the sympathetic nervous system. The local fault may involve the alpha 2-adrenergic receptors, which are most important in reflex sympathetic vasoconstriction. […]
Cardiac sensitivity to the inhibitory effects of chlorpromazine, imipramine and amitriptyline upon formation of flavins.
Author Pinto J, Huang YP, Pelliccione N Date 1/11/1982 Journal Biochem Pharmacol Abstract Chlorpromazine, imipramine and amitriptyline, drugs structurally related to riboflavin, each inhibited the formation in vivo of flavin adenine dinucleotide (FAD) from riboflavin in rat heart at 2-5 mg/kg body weight, doses comparable on a weight basis to those used clinically. All three […]
Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial
Author Meydani SN, Meydani M, Blumberg JB, Leka LS Date 7/5/1997 Journal JAMA Abstract OBJECTIVE: To determine whether long-term supplementation with vitamin E enhances in vivo, clinically relevant measures of cell- mediated immunity in healthy elderly subjects. DESIGN: Randomized, double-blind, placebo-controlled intervention study. SETTING AND PARTICIPANTS: A total of 88 free-living, healthy subjects at least […]
Effects of Lentinus edodes, Grifola frondosa and Pleurotus ostreatus administration on cancer outbreak, and activities of macrophages and lymphocytes in mice treated with a carcinogen, N-butyl-N- butanolnitrosoamine.
Author Kurashige S, Akuzawa Y, Endo F Date 5/1997 Journal Immunopharmacol Immunotoxicol Abstract ICR mice were treated with a carcinogen, N-butyl-N’- butanolnitrosoamine BBN), every day for 8 consecutive weeks and the effects of oral administration of edible mushrooms on the induction of urinary bladder carcinoma and on the activities of macrophages and lymphocytes were studied. […]
Prolactin hyperstimulation in response to thyrotropin-releasing hormone in patients with endometriosis.
Author Muse K Date 10/1982 Journal Fertil Steril Abstract In order to clarify the role of hyperprolactinemia as a possible cause of infertility in patients with endometriosis, baseline serum prolactin (PRL) concentrations and the PRL response to thyrotropin-releasing hormone (TRH) stimulation were measured in 14 infertile women with endometriosis and in 13 normal, fertile women. […]
Inhibition of 5 alpha-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoids.
Author Evans BA, Griffiths K, Morton MS Date 11/1995 Journal J Endocrinol Abstract Isoflavonoids and lignans, constituents of many plant foods, have been proposed as protective agents in those populations with a low incidence of hormone-dependent cancers. They may act by their inhibition of the metabolism of growth-promoting steroid hormones. This report describes the inhibition […]
New Polyhydroxylated Triterpenes from Uncaria tomentosa
Author R. Aquino Date 1990 Journal J Nat Prod Abstract Three novel polyhydroxylated triterpenes have been isolated from Uncaria tomentosa. Their structures were established as 1, 2, and 3 by detailed spectral studies including 1H-13C correlations via long range couplings using the INAPT pulse sequence, nOeds, and 2D 1H-13C direct chemical shift correlation (HETCOR) nmr […]
Release of mast cell mediators into the jejunum by cold pain stress in humans.
Author Santos J, Saperas E, Nogueiras C, Mourelle M, Antolin M, Cadahia A, Malagelada JR. Date 4/1998 Journal Gastroenterology Abstract BACKGROUND & AIMS: The central nervous system regulates gut functions via complex interactions between the enteric nervous and immune systems. The aim of this study was to investigate whether mast cell mediators are released into […]
Multiple sclerosis: fat-oil relationship.
Author Swank RL. Date 9/1991 Journal Nutrition Abstract Between 1949 and 1984, 150 patients with multiple sclerosis consumed low-fat diets. Fat, oil, and protein intakes; disability; and deaths were determined. With a daily fat consumption less than 20.1 g/day (av 17 g/day), 31% died, and average deterioration was slight. A daily intake greater than 20 […]
Effects of gamma-linolenic acid supplementation on pregnant rats fed a zinc-deficient diet
Author Dib A, Carreau JP Date 1987 Journal Ann Nutr Metab Abstract The effects of dietary gamma-linolenic acid supplementation in the form of evening primrose oil were examined in pregnant zinc-deficient rats and subsequently in their newborn pups. This supplementation was beneficial, since it reduced pup mortality, increased mean litter size and maintained appetite throughout […]
