Dose dependency of furosemide-induced sodium excretion.

Author Andreasen F, Lauridsen IN, Hansen FA Date 3/1989 Journal J Pharmacol Exp Ther Abstract Intravenous furosemide doses ranging from 5 to 120 mg were given to healthy young volunteers with and without individualized active rehydration with a sodium chloride solution. Sodium excretion rates and fractional sodium excretions (FENa) percentages were correlated significantly with dose […]

Veinotonic effect, vascular protection, antiinflammatory and free radical scavenging properties of horse chestnut extract.

Author Guillaume M, Padioleau F Date 1/1994 Journal Arzneimittelforschung Abstract ISSN: 0004-4172 Horse chestnut extract (HCE), containing 70% escin, is the main active component of Veinotonyl 75. The aim of this work was to investigate pharmacological properties attempting to elucidate the efficacy of HCE in chronic venous insufficiency. Veinotonic and lymphagogue properties: HCE dose dependently […]

Competitive inhibition of iron absorption by manganese and zinc in humans.

Author Rossander-Hulten L, Brune M, Sandstrom B Date 7/1991 Journal Am J Clin Nutr Abstract Zinc and manganese may interfere with iron absorption because of similar physicochemical properties and shared absorptive pathways. The effects of zinc and manganese on iron absorption were studied in human subjects by using paired observations and a dual-radioisotope method (55Fe […]

Folate mouthwash: effects on established gingivitis in periodontal patients.

Author Pack AR Date 10/1984 Journal J Clin Periodontol Abstract A double blind study was designed to determine the effects of folate mouthwash (MW) on established gingivitis in non-pregnant adults. 60 subjects who had greater than 20 teeth, visible gingival inflammation around greater than 6 teeth, no complicated medical history, currently not receiving periodontal treatment […]

How to characterize an antioxidant: an update.

Author Halliwell B Date 1995 Journal Biochem Soc Symp Abstract The term antioxidant is widely used but rarely defined. One suggested definition is that an antioxidant is ‘a substance that, when present at low concentrations compared with those of an oxidizable substrate, significantly delays or prevents oxidation of that substrate’. Many substances have been suggested […]

Role of magnesium in the pathogenesis and treatment of migraines.

Author Mauskop A, Altura BM. Date 1998 Journal Clin Neurosci Abstract The importance of magnesium in the pathogenesis of migraine headaches is clearly established by a large number of clinical and experimental studies. However, the precise role of various effects of low magnesium levels in the development of migraines remains to be discovered. Magnesium concentration […]

A comparison of the effects of an extract of feverfew and parthenolide, a component of feverfew, on human platelet activity in-vitro.

Author Groenewegen WA, Heptinstall S. Date 8/1990 Journal J Pharm Pharmacol Abstract Extracts of the herb feverfew inhibit human blood platelet aggregation and secretion induced by a number of agents in-vitro and this may relate to the beneficial effects of feverfew in migraine. We previously identified several compounds with antisecretory activity in human blood platelets […]