Low brain magnesium in migraine.
Author Ramadan NM, Halvorson H, Vande-Linde A Date 10/1989 Journal Headache Abstract Brain magnesium was measured in migraine patients and control subjects using in vivo 31-Phosphorus Nuclear Magnetic Resonance Spectroscopy. pMg and pH were calculated from the chemical shifts between Pi, PCr and ATP signals. Magnesium levels were low during a migraine attack without changes […]
Parthenolide inhibits the contractile responses of rat stomach fundus to fenfluramine and dextroamphetamine but not serotonin.
Author Bejar E Date 1/1996 Journal J Ethnopharmacol Abstract The isolated rat stomach fundus preparation, a sensitive bioassay to evaluate serotonin-(5-HT) like activity, was used as a model to study the effects of parthenolide (PAR), a component to Tanacetum parthenium (feverfew), on 5-HT storage, release and stimulation of the 5-HT2B receptor. Cumulative-concentration response curves to […]
Essential fatty acid treatment prevents nerve ischaemia and associated conduction anomalies in rats with experimental diabetes mellitus
Author Stevens EJ, Lockett MJ, Carrington AL Date 5/1993 Journal Diabetologia Abstract In rats with 6 weeks streptozotocin-diabetes there was a 53% reduction in sciatic nerve laser Doppler flux compared to controls (p < 0.01). Treatment of a parallel group of diabetic rats with evening primrose oil, by dietary admixture throughout the protocol, prevented this […]
Hypoglycemic activity of polypeptide-p from a plant source.
Author Khanna P, Jain SC, Panagariya A Date 11/1981 Journal J Nat Prod Abstract A hypoglycemic peptide, Polypeptide-p, has been isolated from fruit, seeds, and tissue of Momordica charantia Linn (bitter gourd). Amino acid analysis indicates a minimum molecular weight of approximately 11,000 (166 residues). Polypeptide-p is a very effective hypoglycemic agent when administered subcutaneously […]
Oral intake of phosphorus can determine the serum concentration of 1,25-dihydroxyvitamin D by determining its production rate in humans.
Author Portale AA, Halloran BP, Murphy MM Date 1/1986 Journal J Clin Invest Abstract Changes in the oral intake of phosphorus could induce the reported changes in the serum concentration of 1,25-dihydroxyvitamin D (1,25- (OH)2D) by inducing changes in its production rate (PR) or metabolic clearance rate (MCR), or both. To investigate these possibilities, we […]
Capsaicin-sensitive mechanisms and experimentally induced duodenal ulcers in rats.
Author Maggi CA, Evangelista S, Abelli L Date 7/1987 Journal J Pharm Pharmacol Abstract The incidence and degree of cysteamine- or dulcerozine-induced duodenal ulcers are increased by systemic capsaicin desensitization (50 mg kg-1 s.c. 4 days before) in adult rats. Acute administration of capsaicin, but not neurokinins or CGRP, produced a small but distinct plasma […]
In vitro inactivation of human immunodeficiency virus by ascorbic acid.
Author Rawal BD, Bartolini F, Vyas GN Date 3/1995 Journal Biologicals Abstract In vitro inactivation of cell-free human immunodeficiency virus (CFHIV) was investigated by mixing replication-competent virions with aliquots of a culture medium (RPMI) containing increasing amounts (62.5-500 micrograms/ml) of ascorbic acid (AA) at pH7. Similarly, mixtures of CFHIV and 500 micrograms/ml AA in whole […]
NK immunomodulatory function in 27 cancer patients by MGN-3, a modified arabinoxylane from rice bran .
Author Ghoneum M, Namatalla G Date 4/1996 Journal Proc Annu Meet Am Assoc Cancer Res Abstract MGN-3 immunomodulatory function was examined in 27 cancer patients. MGN-3 is an arabinoxylane from rice bran that has been enzymatically modified by Hyphomycetes mycelia. The patients had different types of advanced malignancies: 7 patients had breast CA, 7 prostate, […]
Immunohistochemical assessment of superoxide dismutase expression in the endometrium in endometriosis and adenomyosis.
Author Ota H Date 7/1999 Journal Fertil Steril Abstract OBJECTIVE: To determine the expression of superoxide dismutase (SOD) in the endometrium during the menstrual cycle in endometriosis and adenomyosis. DESIGN: Immunohistochemical identification of SOD in endometrial tissues using the monoclonal antibody. SETTING: Department of obstetrics and gynecology in a university hospital. PATIENT(S): The subjects were […]
The estrogenic and antiestrogenic activities of phytochemicals with the human estrogen receptor expressed in yeast.
Author Collins BM, McLachlan JA, Arnold SF Date 4/1997 Journal Steroids Abstract We have used the expression of the human estrogen receptor (hER) and two estrogen response elements linked to the lacZ gene in yeast (YES) to study the estrogenic and antiestrogenic activities of various phytochemicals. Coumestrol, alpha-zearalenol, or genistein could produce beta-galactosidase activity comparable […]
