Biotherapeutic agents. A neglected modality for the treatment and prevention of selected intestinal and vaginal infections
Author Elmer GW Date 3/1996 Journal JAMA Abstract OBJECTIVE: To evaluate the potential of biotherapeutic agents (microorganisms with therapeutic properties) for the prevention and/or treatment of selected intestinal and vaginal infections. DATA SOURCES: The MEDLINE database was searched for all relevant articles published between 1966 and September 1995. Search terms used were biotherapeutic agent, probiotic, […]
The controversy surrounding the pathogenesis of the multiple sclerosis lesion.
Author Lucchinetti CF, Rodriguez M Date 7/1997 Journal Mayo Clin Proc Abstract The main issues in multiple sclerosis research revolve around four fundamental questions. (1) What initiates the disease-that is, autoimmune T cells, a virus, or a toxin? (2) Is the inflammatory response primary to the development of demyelination, or is it a secondary response […]
Vitamin B12 metabolism and massive-dose methyl vitamin B12 therapy in Japanese patients with multiple sclerosis.
Author Kira J, Tobimatsu S, Goto I Date 2/1994 Journal Intern Med Abstract Serum vitamin B12 levels and unsaturated vitamin B12 binding capacities were measured in 24 patients with multiple sclerosis (MS), 73 patients with other neurological disorders and 21 healthy subjects. There was no decrease in the vitamin B12 levels, however, a significant decrease […]
Effect of Ganoderma lucidum on postherpetic neuralgia.
Author Hijikata Y, Yamada S Date 1998 Journal Am J Chin Med Abstract Administration of hot water soluble extracts of Ganoderma lucidum (GI) (36 to 72 g dry weight/day) decreased pain dramatically in two patients with postherpetic neuralgia recalcitrant to standard therapy and two other patients with severe pain due to herpes zoster infection.
Preventive effect of gomisin A, a lignan component of shizandra fruits, on acetaminophen-induced hepatotoxicity in rats.
Author Yamada S, Murawaki Y, Kawasaki H Date 14/9/1993 Journal Biochem Pharmacol Abstract The preventive effect of gomisin A, a lignan component of shizandra fruits, on acetaminophen-induced hepatotoxicity in rats was examined by histological and biochemical analysis. Acetaminophen at a dose of 750 mg/kg was administered to male Wistar rats with or without pretreatment with […]
Free radical theory of aging: history.
Author Harman D. Date 1992 Journal EXS Abstract Aging is the accumulation of changes responsible for the sequential alterations that accompany advancing age and the associated progressive increases in the chance of disease and death. These changes can be attributed to disease, environment, and the inborn aging process. The aging process is now the major […]
Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group
Author Seddon JM, Ajani UA, Sperduto RD Date 9/11/1994 Journal JAMA Abstract OBJECTIVE– To evaluate the relationships between dietary intake of carotenoids and vitamins A, C, and E and the risk of neovascular age- related macular degeneration (AMD), the leading cause of irreversible blindness among adults. DESIGN– The multicenter Eye Disease Case- Control Study. SETTING– […]
Cross sectional study of effects of drinking green tea on cardiovascular and liver diseases
Author Imai K, Nakachi K Date 18/3/1995 Journal BMJ Abstract OBJECTIVE–To investigate the association between consumption of green tea and various serum markers in a Japanese population, with special reference to preventive effects of green tea against cardiovascular disease and disorders of the liver. DESIGN–Cross sectional study. SETTING–Yoshimi, Japan. SUBJECTS–1371 men aged over 40 years […]
Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica.
Author Maquart FX, Bellon G, Gillery P Date 1990 Journal Connect Tissue Res Abstract The drug “Titrated Extract from Centella asiatica” (TECA), used for its stimulating properties on the healing of wounds, is a mixture of 3 terpenes extracted from a tropical plant: asiatic acid (30%, w/w), madecassic acid (30%, w/w) and asiaticoside (40%, w/w). […]
The importance of nutrition among the risk factors in varicose veins
Author Melet JJ Date 7/1981 Journal Phlebologie Abstract The author reminds us that varicose veins involve a large social and financial cost. He states the the etiopathogenic hypotheses commonly suggested have not been confronted with geographic pathological data and that consequently they are of little value. A thorough study of the epidemiological data and clinical […]
