Home > Safety > Interaction And Depletions > Herbal Monograph (Consumer) > Bitter Melon : interaction with Diabetic / Hypoglycemic medications

Bitter Melon : interaction with Diabetic / Hypoglycemic medications

Interaction type:
Interactions

Interaction rating:
Potential/Theoritical

Bitter melon fruit may decrease blood sugar which may alter the effects of this medication and possibly the dose needed for treatment. Use with caution. (1) (2)

These drugs include Insulin, glyburide, glipizide, metformin, rosiglitazone, pioglitazone, glimepiride, tolbutamide, tolazamide, acarbose, acetohexamide, chlorpropamide, miglitol, repaglinide, nateglinide

References

View Abstract: Ali L, et al. Studies on Hypoglycemic Effects of Fruit Pulp, Seed, and Whole Plant of Momordica charantia on Normal and Diabetic Model Rats. Planta Med. Oct1993;59(5):408-12.
View Abstract: Sarkar S, et al. Demonstration of the Hypoglycemic Action of Momordica Charantia in a Validated Animal Model of Diabetes. Pharmacol Res. Jan1996;33(1):1-4.

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