Interaction type:
Interactions
Interaction rating:
Potential/Theoritical
Based on pharmacology: In vitro studies have reported that constituents contained in devil’s claw tubers have antiarrhythmic activity which may alter the effects of these medications and possible the dose needed for treatment. Use with caution. (1) These drugs include amiodarone, bretylium tosylate, adenosine, dofetilide, propafenone, lidocaine, tocainide, flecainide, ibutilide fumarate, moricizine, quinidine, disopyramide, procainamide, mexiletine, verapamil, digoxin, propranolol, sotalol, esmolol, acebutolol.
References
- View Abstract: Costa De Pasquale R, Busa G, Circosta C, Iauk L, Ragusa S, Ficarra P, Occhiuto F. A drug used in traditional medicine: Harpagophytum procumbens DC. III. Effects on hyperkinetic ventricular arrhythmias by reperfusion. J Ethnopharmacol. May 1985;13(2):193-9.
