How Vitamin C interacts with Loop diuretics


Interaction type:
Depletions

Interaction rating:
Study Supported

Furosemide has been reported to cause an increased urinary excretion of vitamin C. Other loop diuretics would be expected to have a similar effect based on pharmacology. Supplementation with the affected nutrient may be necessary. (1) These drugs include furosemide, bumetanide, ethacrynic acid, torsemide.

References

  1. View Abstract: Mydlik M, et al. The Effect of Furosemide on Urinary Excretion of Oxalic Acid, Vitamin C and Vitamin B6 in Chronic Kidney Failure. Vnitr Lek. 1998;44(3):127-31.