Labdane Diterpene from Croton ensifolius

Author

ROZA DIANITA, JALIFAH LATIP, BOHARI M. YAMIN & IKRAM M. SAID

Proceeding

The 21st Annual Seminar of the Malaysian Natural Product Society.(Herbal Medicine:Natural Products Society), Palm Garden, Putrajaya Malaysia.

Date

22/11/2005

Keyword

Labdane diterpene, Croton ensifolius, Euphorbiaceae, 13-epi-sclareol.

Abstract

A labdane type diterpene was isolated from the leaves ofCroton ensifoliusMerr (Euphorbiaceae). The compound was isolated from 90% methanol fraction by using vacuum liquid chromatography, conventional column chromatography, and radial chromatography as colourless crystals with melting point 126-128 ÂșC. The spectroscopic data of the compound such as mass, ultraviolet, infrared, and nuclear magnetic resonance suggested that the compound was 13-epi-sclareol. The structure was confirmed by X-ray crystallographic data.