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Conservation

Compilation of herbal plants (description, geographical distribution, taxonomy, line drawings), biodiversity and herbarium.

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Research & Publication

Description of herbal and T&CM research, searchable publication and process from medicinal plant discovery to clinical trial in producing a high-quality registered herbal drug.

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Traditional & Complementary Medicine (T&CM)

 

Definition and description of therapies, policy, training and education, research in the practise of (T&CM) and integrated medicine system.           

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Forthcoming Events

3rd International Conference and Exhibition on Pharmaceutical Nanotechnology and Nanomedicine

From Mon, 24. February 2020 Until Tue, 25. February 2020

21st Interntaional Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems

From Wed, 11. March 2020 Until Thu, 12. March 2020

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From Mon, 23. March 2020 Until Tue, 24. March 2020

2nd International Conference on Bio-Pharmaceuticals

From Wed, 25. March 2020 Until Thu, 26. March 2020

How St. John's Wort interacts with Antidepressants

Interaction type: Interactions

Interaction rating: Study Supported

Animal studies and human case reports have reported that St. John's wort may increase the effects of these medications and possibly change the dose needed for treatment. Use with caution. (1) (2) (3) (4) (5) (6) (7)

These drugs include fluoxetine, fluvoxamine, paroxetine, sertraline, amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, trimipramine, maprotiline, mirtazapine, trazodone, bupropion, venlafaxine, nefazodone, citalopram, protriptyline, phenelzine, tranylcypromine, isocarboxazid

References

  1. View Abstract: Muller WE, et al. Effects of Hypericum Extract (LI 160) in Biochemical Models of Antidepressant Activity. Pharmacopsychiatry. 1997;30(Supp 2):102-07.
  2. View Abstract: Linde K, et al. St. John's Wort for Depression--An Overview and Meta-analysis of Randomised Clinical Trials. BMJ. 1996;313m:253-58.
  3. Demott K. St. John’s Wort Tied to Serotonin Syndrome. Clin Psychiatry News. 1998;26:28.
  4. Suzuki O, et al. Inhibition of Monoamine Oxidase by Hypericin. Planta Medica. 1984;50:272-74.
  5. View Abstract: Bladt S, et al. Inhibition of MAO by Fractions and Constituents of Hypericum Extract. J Geriatric Psychiatry and Neurology. 1994;7:S57-S59.
  6. Gordon JB. SSRIs and St.John's Wort: possible toxicity? Am Fam Physician. Mar1998;57(5):950,953.
  7. View Abstract: Lantz MS, Buchalter E, Giambanco V. St. John's wort and antidepressant drug interactions in the elderly. J Geriatr Psychiatry Neurol. 1999;12(1):7-10.

Explore Further

Consumer Data

Consumer data including medicinal herbs, dietary supplement monographs, health condition monographs and interactions and depletions.                                    

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Professional Data

Professional data organized into medicinal herbs, dietary supplement monographs, health condition monographs, T&CM herbs, formulas, health conditions, interactions and depletions.

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International Data

We offer International linkages to provide extensive content pertaining to many facets of T&CM as well as Integrated Medicine. Please register for access.    

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