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How Zinc interacts with penicillamine

Interaction type: Depletions

Interaction rating: Study Supported

This medication is reported to cause increased elimination of zinc and copper in the urine. Supplementation with the affected nutrient(s) may be necessary. (1)


  1. View Abstract: Lu JX, et al. Penicillamine: Pharmacokinetics and Differential Effects on Zinc and Copper Status in Chicks. J Nutr. Feb1992;122(2):355-62.