How Arginine interacts with Nitrates

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Based on Pharmacology: Arginine could potentiate the vasodilator effects of nitrates which may alter the effects of these medications and possibly the dose needed for treatment. Use with caution. (1)

These drugs include nitroglycerin (various dosage forms), isosorbide mononitrate, isosorbide dinitrate, amyl nitrate


  1. View Abstract: Tentolouris C, Tousoulis D, Goumas G, et al. L-Arginine in Coronary Atherosclerosis. Int J Cardiol. Sep2000;75(2-3):123-8.