Gou Ji

Cibotii Rhizoma, Cibotium

Dosage

6-12g.

Chemical Composition

Pterosin R; Onitin; Onitin-2'-O-(-D-glucoside; Onitin-2'-O-(-D-alloside; Ptaquiloside; Pterosin Z. (1) , (2)

Pharmacology

Effects on the cardiac muscle

One-time abdominal injection of Gou Ji solution to mice at the dosage of 20-30g/kg does not significantly affect their myocardial absorption of 86Rb; administering the solution daily for 14 consecutive days, however, increases the myocardial absorption of 86Rb by 54%, indicating that Gou Ji increases mice's myocardial nutrient blood volume, and this effect is cumulative with repeat administration. (3)

Anti-neoplastic effect

Experiments show that administered by abdominal injection, alcohol-based extract of Gou Ji with a 70% concentration can prolong the life of mice inoculated with Aldrin's ascitic carcinoma and S180 ascitic sarcoma, and inhibit deoxycytosine from entering sarcoma cells (with a 98% inhibition rate). (4)

References

  1. Yuan Zhong, et al. Journal of Chinese Materia Medica. 1996;27(2):76.
  2. Editorial Committee of Chinese Materia Medica. State Drug Administration of China. Chinese Materia Medica. Shanghai: Science and Techonology Press; 1998.
  3. Zhang Bao Heng, et al. TCM Bulletin. 1985;10(2):42.
  4. Xu Zhong Yuan, et al. Journal of Chinese Herbal Material. 1999;22(12):662-663.