In vitro inhibitory activities of 8-Hydroxyquinoline derivatives on dengue and West Nile virus: A descriptive review.

 

Title Outcome parameters Types and total included study Findings
In vitro inhibitory activities of 8-Hydroxyquinoline derivatives on dengue and West Nile virus: A descriptive review. The ability of 8-Hydroxyquinoline derivatives to inhibit West Nile Virus or Dengue virus replication strain

Total 8 papers were included which consists of 6 papers: In vitro studies on 8-Hydroxyquinoline research on dengue virus, West Nile virus, and few other  pathogens                2 review papers: potential antiviral drug target based on the molecular structure of flavivirus

Currently, there are limited references available in order to suggest or dispute the use of 8-Hydroxyquinoline as a potential anti-dengue agent. Thus, further investigations with a proper methodology and outcomes need to be conducted to yield results that can be translated into in vivo and clinical studies.

Read More