Anti-Inflammatory Properties Of Eugenol And Ginger Oil In Rats Arthritis Induced By Mycobacterial Adjuvant


I.N. Sharma. S.S. Amrah & K.C. Srivastava*, Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian. Kelantan, Malaysia, *Department of Environmental Medicine, Institute of Community Health, Odense University, Odense, Denmark.


Trends in Traditional Medicine Research, Proceedings of the International Conference on the Use of Traditional Medicine & Other Natural Products in Health Care




Adjuvant arthritis, inflammation, eugenol, ginger oil, anti-inflammatory,


The present study examined the anti-inflammatory properties of eugenol and ginger oil in chronic adjuvant-induced arthritis in rats. Eugenol (33 mg/kg) and ginger oil (33 mg/kg) administered orally for 26 days caused significant (p < 0.05 to p < 0.01) reduction of paw and knee joint inflammation when compared with the nontreated arthritic rats. These findings suggest that eugenol and ginger oil might possess potent anti-inflammatory activities.