Characterisation of the central nervous depressant activity of a commercially available valerian root extract.

Author

Leuschner J, Muller J, Rudmann M

Date

6/1993

Journal

Arzneimittelforschung

Abstract

The evaluation of a commercially available valerian root extract (Valdispert) revealed pronounced sedative properties in the mouse with respect to a reduction in motility and an increase in the thiopental sleeping-time. A direct comparison with diazepam and chlorpromazine revealed a moderate sedative activity for the tested extract. The extract showed only weak anticonvulsive properties.