image
Conservation

Compilation of herbal plants (description, geographical distribution, taxonomy, line drawings), biodiversity and herbarium.

Read More
image
Research & Publication

Description of herbal and T&CM research, searchable publication and process from medicinal plant discovery to clinical trial in producing a high-quality registered herbal drug.

Read More
 
Traditional & Complementary Medicine (T&CM)

 

Definition and description of therapies, policy, training and education, research in the practise of (T&CM) and integrated medicine system.           

Read More

 

News Update

Announcement & Advertisement

Forthcoming Events

International Conference on Natural Products (ICNP) 2020

From Mon, 29. June 2020 Until Tue, 30. June 2020

13th National Conference for Clinical Research (NCCR) 2020

From Wed, 8. July 2020 Until Fri, 10. July 2020

The 10th International Congress of Natural Products Research (ICNPR) 2020

From Sat, 25. July 2020 Until Thu, 30. July 2020

Asian Symposium on Medicinal Plants and Spices XVII (2020)

From Tue, 18. August 2020 Until Wed, 19. August 2020

4th Interntaional Conference on Natural Products and Medicinal Plants Research

From Fri, 25. September 2020 Until Sat, 26. September 2020

Inhibition of morphine tolerance and dependence by Withania somnifera in mice.

Author

Kulkarni SK, Ninan I

Date

8/1997

Journal

J Ethnopharmacol

Abstract

Chronic treatment with Withania somnifera (Ws) (family: Solanaceae, 100 mg/kg) commercial root extract followed by saline on days 1-9 failed to produce any significant change in tailflick latency from the saline pretreated group in mice. However, repeated administration of Ws (100 mg/kg) for 9 days attenuated the development of tolerance to the analgesic effect of morphine (10 mg/kg). Ws (100 mg/kg) also suppressed morphine-withdrawal jumps, a sign of the development of dependence to opiate as assessed by naloxone (2 mg/kg) precipitation withdrawal on day 10 of testing.

Explore Further

Consumer Data

Consumer data including medicinal herbs, dietary supplement monographs, health condition monographs and interactions and depletions.                                    

Read More
Professional Data

Professional data organized into medicinal herbs, dietary supplement monographs, health condition monographs, T&CM herbs, formulas, health conditions, interactions and depletions.

Read More
International Data

We offer International linkages to provide extensive content pertaining to many facets of T&CM as well as Integrated Medicine. Please register for access.    

Read More