Articles

The efficacy and safety of glucosamine sulfate in the treatment of gonarthritis

Author

Giordano N, Nardi P, Senesi M, Palumbo F

Date

3/1996

Journal

Clin Ter

Abstract

This study was performed to evaluate the therapeutic efficacy and tolerability of glucosamine sulfate in patients with gonarthritis. During the 12-month study period, the signs and symptoms of the disease were evaluated, as well as the dosage of the urinary pyridinoline. In this trial, we demonstrated that glucosamine sulfate has a chondroprotective activity, which was significant after the first 3 months of therapy. Moreover, this study showed that the side effects due to glucosamine sulfate were mild to moderate and did not require discontinuation of the drug.