[Effect of ginsenosides Rb1 and Rg1 on lipid peroxidation of rat in vitro].


Huang YS




Zhongguo Yi Xue Ke Xue Yuan Xue Bao


Ginsenosides Rb1 and Rg1 were found to inhibit to some degree both VitC-NADPH and Fe2(+)-cysteine induced lipid peroxidation of rat liver and brain microsomes. However, the inhibitory effect of Rb1 and Rg1 was obvious in liver microsomes, especially in Vit C-NADPH induced lipid peroxidation of liver microsomes. Besides, Rb1 was shown to be more potent than Rg1 in inhibiting VitC-NADPH or Fe2(+)-cysteine induced lipid peroxidation. The inhibitory effect of Rb1 on VitC-NADPH induced lipid peroxidation was similar to that of VitE at the same concentration.