How Coleus interacts with Antihistamines

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Studies report that coleus may act in the body like some of these medications, which may alter the effects of these medications and possibly the dose needed for treatment. Use with caution. (1)

These drugs include diphenhydramine, chlorpheniramine, azelastine, cetirizine, fexofenadine, loratadine, desloratadine, brompheniramine, dexchlorpheniramine, clemastine, promethazine, hydroxyzine, azatadine, cyproheptadine, phenindamine


  1. View Abstract: Marone G, et al. Inhibition of IgE-mediated Release of Histamine and Peptide Leukotriene from Human Basophils and Mast Cells by Forskolin. Biochem Pharmacol. 1987;36(1):13-20.