How Black Cohosh interacts with Estrogen and estrogen-like medications

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Black cohosh has estrogen-like activity which may alter the effects of these medications and possibly the dose needed for treatment. Use with caution. (1) (2)

These drugs include conjugated estrogens, estradiol, estrone, esterified estrogens, estropipate, ethinyl estradiol, raloxifene

References

  1. Jarry H, et al. The Endocrine Effects of Constituents of Cimicifuga racemosa. 2. In Vitro Binding of Constituents to Estrogen Receptors. Planta Med. Aug1985;4:316-19.
  2. View Abstract: Duker EM, et al. Effects of Extracts from Cimicifuga racemosa on Gonadotropin Release in Menopausal Women and Ovariectomized Rats. Planta Med. Oct1991;57(5):420-24.