How Goldenseal interacts with paclitaxel

Interaction type: Interactions

Interaction rating: Study Supported

A laboratory study reported that berberine, a chemical in goldenseal, may decrease the effect of this medication. Use with caution. (1)


  1. View Abstract: Lin HL, et al. Berberine Modulates Expression of Mdr1 Gene Product and The Responses of Digestive Track Cancer Cells to Paclitaxel. Br J Cancer. Oct1999;81(3):416-22.