How Passionflower interacts with Antidepressants

Interaction type: Interactions

Interaction rating: Potential/Theoritical

Animal studies report that passionflower may cause sedation, which may enhance the effects of these medications and possibly the dose needed for treatment. Use with caution. (1)

These drugs include fluoxetine, fluvoxamine, paroxetine, sertraline, amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, trimipramine, maprotiline, mirtazapine, trazodone, bupropion, venlafaxine, nefazodone, citalopram, protriptyline, phenelzine, tranylcypromine, isocarboxazid

References

  1. Speroni E, et al. Neuropharmacological Activity of Extracts from Passiflora incarnata. Planta Med. Dec1988;54(6):488-91.