How Iron interacts with Bile acid sequestrants

Interaction type: Interactions

Interaction rating: Study Supported

These medications decrease the absorption of iron. Supplementation with the affected nutrient may be necessary. (1) (2)

These drugs include cholestyramine, colestipol, colesevelam


  1. View Abstract: Leonard JP, et al. In Vitro Binding of Various Biological Substances by Two Hypocholesterolaemic Resins. Cholestyramine and Colestipol. Arzneimittelforschung. 1979;29(7):979-81.
  2. Thomas FB, et al. Inhibition of Iron Absorption by Cholestyramine. Demonstration of Diminished Iron Stores Following Prolonged Administration. Am J Dig Dis. Mar1972;17(3):263-69.