How Magnesium interacts with penacillamine

Interaction type: Interactions

Interaction rating: Study Supported

This medication has been reported to bind with magnesium, which may decrease the absorption of both the drug and iron. Supplementation with the affected nutrient and adjustment in the drug dosage may be necessary. (1)


  1. View Abstract: Seelig MS. Auto-immune Complications of D-Penicillamine - A Possible Result of Zinc and Magnesium Depletion and of Pyridoxine Inactivation. J Am Coll Nutr. 1982;1(2):207-14.