How Vitamin B12 interacts with Bile acid sequestrants

Interaction type: Depletions

Interaction rating: Study Supported

These medications decrease the absorption of vitamin B12. Supplementation with the affected nutrient may be necessary. (1)

These drugs include cholestyramine, colestipol, colesevelam


  1. View Abstract: Leonard JP, et al. In vitro Binding of Various Biological Substances by Two Hypocholesterolaemic Resins. Cholestyramine and Colestipol. Arzneimittelforschung. 1979;29(7):979-81.