How Vitamin B6 interacts with hydralazine

Interaction type: Depletions

Interaction rating: Study Supported

Animal and human studies have reported that this medication can decrease the levels of this vitamin in the body. Supplementation with the affected nutrient may be necessary. (1) (2)


  1. View Abstract: Vidrio H. Interaction with Pyridoxal as a Possible Mechanism of Hydralazine Hypotension. J Cardiovasc Pharmacol. Jan1990;15(1):150-56.
  2. View Abstract: Shigetomi S, Kuchel O. Defective 3,4-dihydroxyphenylalanine Decarboxylation to Dopamine in Hydralazine-treated Hypertensive Patients May be Pyridoxine Remediable. Am J Hypertens. Jan1993;6(1):33-40.