How Vitamin C interacts with copper

Interaction type: Depletions

Interaction rating: Potential/Theoritical

Studies in animals and humans have reported that high doses of vitamin C may decrease the absorption of copper from the digestive tract. Supplementation with the affected nutrient may be necessary. (1) (2)


  1. Van Campen D, Gross E. Influence of Ascorbic Acid on the Absorption of Copper by Rats. J Nutr. Aug1968;95(4):617-22.
  2. View Abstract: Finley EB, Cerklewski FL. Influence of Ascorbic Acid Supplementation on Copper Status in Young Adult Men. Am J Clin Nutr. Apr1983;37(4):553-6.