How Vitamin D interacts with Corticosteroid medications

Interaction type: Depletions

Interaction rating: Study Supported

A study showed that children taking corticosteroids for a long period of time had decreased levels of the active form of vitamin D and decreased bone density. Supplementation with the affected nutrient may be necessary. (1)

These drugs include prednisone, hydrocortisone, methylprednisolone, prednisolone, betamethasone, budesonide, triamcinolone, dexamethasone, cortisone, beclomethasone, flunisolide, fluticasone, fludrocortisone, mometasone


  1. View Abstract: Chesney RW, et al. Reduction of Serum-1, 25-dihydroxyvitamin-D3 in Children Receiving Glucocorticoids. Lancet. Nov1978;2(8100):1123-25.